A small reduction has been found. There may be a larger effect for those with dyslipidemia, but more research is needed to evaluate this and determine its usefulness. Overall, it doesn't seem to have a meaningful effect. More research for those with dyslipidemia could be potentially useful. While some studies have found a reduction, overall it doesn't appear to be reliable or meaningful.
Two studies have found fairly potent effects of mg of saffron extract. More research is needed to strengthen these findings, and it remains promising but speculative. Basophil Count. Basophil count has been noted to mildly decrease following saffron supplementation alongside a reduction in IgM concentrations.
The aroma of saffron has been noted to reduce cortisol concentrations to a mild degree in otherwise healthy women, and this occurred alongside a reduction in state anxiety. The aroma of saffron appears to cause a mild increase in circulating estrogen concentrations in otherwise healthy women following 20 minutes of exposure. The reduction seems to be small overall, but it does seem to have some potential to reduce CRP.
Immunoglobulin G. An increase in IgG concentrations has been noted to occur with saffron supplementation alongside a decrease in IgM and no influence on IgA.
Immunoglobulin M. A decrease in IgM concentrations has been noted to occur following supplementation of saffron. Monocyte Count. Supplementation of saffron appears to be able to cause a mild increase in monocyte concentrations in serum. Red Blood Cell Count. Mixed evidence, some studies suggest a reduction, which may be due to toxicity with a high dose, but it's unclear.
Serum Platelets. Supplementation of 60 mg saffron was able to reduce platelet counts in serum following eight weeks of exposure increasing in magnitude until study cessation at 26 weeks thought to be related to toxicity. Other studies didn't find effects at 30 mg of an extract or mg of saffron powder. Sexual Function. One study found an improvement for women taking SSRIs. The study that evaluated men taking SSRIs didn't find an effect, though one in general erectile dysfunction with diabetes found an improvement.
Sperm Quality. Inconsistent effects but an improvement is possible, though it's not clear how likely it is yet. Mixed evidence on the efficacy of saffron, but it is possible that supplementation could delay an increase in symptoms without a therapeutic effect. Visual Acuity. Supplementation of saffron appears to increase visual acuity in persons with age-related macular degeneration. White Blood Cell Count. A decrease in white blood cell count has been noted with supplementation of saffron at 60mg for over eight weeks.
Mixed evidence, it doesn't seem to have much of an effect, though the study that found an effect used a much larger dose of Blood Pressure. Creatinine does not appear to be influenced in serum following supplementation of saffron.
Ejaculate Volume. Saffron does not appear to influence ejaculate volume in men with infertility. Eosinophil count. Eosinophil concentrations are not affected by saffron supplementation in otherwise healthy persons, though a reduction in allergic asthma was found, which is likely a good sign. Follicle-Stimulating Hormone. FSH is unaffected in infertile men given 60mg saffron daily over the course of 26 weeks.
Food Intake. In one study, secondary to reducing snacking thought to be via increasing satiety from meals saffron appeared to reduce overall food intake. In another, it didn't, however. More research is needed. Overall there didn't appear to be a meaningful effect. It is possible that an effect could be seen for those with type 2 diabetes but more high-quality research is needed.
Most studies don't support an effect. Hemoglobin has been noted to be decreased in one study and thought to be related to possible toxic effects of moderately high dose saffron 60 mg for more than 8 weeks.
Immunoglobulin A. No significant influence on circulating IgA concentrations following saffron ingestion. Luteinizing Hormone. Neutrophil Count. Supplementation of 60mg saffron for 26 weeks did not significantly influence prolactin in infertile men. Seminal Motility. The best evidence to date does not support a role for saffron supplementation in increasing seminal motility. Sperm Count. Saffron supplementation does not appear to be effective in increasing sperm count in infertile men.
Neither aromatherapy nor oral supplementation appear to significantly influence testosterone concentrations in serum. Waist circumference. Some studies have found an effect but most didn't, and it seems unlikely to have much of an impact in the short-term.
Hot Flashes. Muscle Soreness. Cervix Readiness Pregnancy. One study found an increase after 24 hours and just after starting uterine contractions. Creatine Kinase-MB. One study found a reduction in conjunction with an improvement in fibromyalgia symptoms.
Symptoms of Fibromyalgia. Symptoms of Rheumatoid Arthritis. Anti-HSP70 Antibodies. Bleeding Time. Cancer Metastasis. Cognitive Decline. Appears to improve cognition in those with Alzheimer's or mild cognitive impairment in two studies. Erythrocyte Sedimentation Rate. Mixed evidence, the negative study was in schizophrenia and the positive study was in rheumatoid arthritis, so it may have more of an effect in inflammatory conditions.
But more research is needed. General Oxidation. Intraocular Pressure. Lactate Dehydrogenase. Lean Mass. Lipid Peroxidation. The effect seems small and inconsistent but evidence supports some subtle effect.
Lung Function. Lymphocyte Count. Malondialdehyde MDA. Oxidation of LDL. Supplementation of saffron appears to be capable of reducing LDL oxidation when tested ex vivo in both healthy controls and persons with cardiovascular disease, although to a mild degree.
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Weight loss story: "At 28, I weighed more than my mother and this is how I lost weight". Stomach cancer. Whooping cough. Count: We have sent you a verification email. To verify, just follow the link in the message. Created: Oct 22, , IST. If you are a money-saving Indian like me, then this article might help you.
I know that saffron is not exactly the cheapest ingredient, but if it's available in your kitchen, then give it a try. As Indians, we have underrated our kitchens for far too long and I am also guilty of that. However, now that I am living miles and miles away from my country, I have finally realised the worth of many super cheap, everyday ingredients readily available in the kitchen, which can help you lose weight, get great skin and feel good.
When I shifted, I thought that maybe goji berries, chia seeds, quinoa, lettuce, green and berry smoothies were the answer to my skin and weight issues. Since the West has aggressively instrumented the use of these veggies, seeds, fruits and made us believe that they are the answer to our troubles, I, like any other Indian, fell for the same trap.
But, now that I am finally here, back to eating my desi spices and drinking my cardamom water, I have understood that it's all a sham. And how did I get to this? When an Iranian friend gifted me saffron, which is extensively used in her and my country. Comments 0. Be the first one to comment. Read All Comments Post a Comment. Visual Stories Right arrow. Life Style Positive affirmations for all single people out there.
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Develop and improve products. List of Partners vendors. You may know of saffron as the spice used to flavor dishes like bouillabaisse and paella, but saffron extract has a long and varied history in herbal medicine spanning over 2, years. According to a review study from , it's been used in various countries to treat skin disease, respiratory issues, poor vision, pain, mental illness, gynecological problems, erectile dysfunction, and infections.
Derived from the crocus flower Crocus sativus , saffron is a perennial stemless herb that's largely cultivated in Iran and some other countries including Spain, India, and Greece.
The flower of C. It takes about 36, flowers, which are harvested by hand, to yield a single pound of stigmas. Over , dried stigmas obtained from about 70, flowers yield grams of pure saffron. Hence the reason it's often referred to as "Red Gold. More than chemicals are present in saffron, but the key ones are crocetin and crocin, picrocrocin, and safranal, which are responsible for saffron's color, taste, and odor.
Saffron has been shown to be helpful in several diseases, and according to a review study from , it's time to move into more advanced stages of study or to even develop a drug for the use of saffron in the treatment of depression and Alzheimer's disease. Preliminary studies suggest this culinary spice is helpful in treating mood disorders. In a double-blind, placebo-controlled study, 60 adults with anxiety and depression received either 50 milligrams mg of saffron or a placebo twice daily for 12 months.
In a study published in the Journal of Affective Disorders , adults with major depressive disorder took crocin an active constituent of saffron or a placebo along with Prozac fluoxetine , Zoloft sertraline , or Celexa citalopram , selective serotonin reuptake inhibitor drugs SSRI that are commonly used for depression.
Results revealed that the group taking crocin had significantly improved scores on self-reported assessments compared to those taking the placebo. In a study published in the Journal of Affective Disorders , adults with mild-to-moderate depression took either a saffron supplement or Prozac daily for six weeks. A review of six clinical trials with placebo or antidepressant controls published in the Human Psychopharmacology in concluded that "research conducted so far provides initial support for the use of saffron for the treatment of mild-to-moderate depression.
When studied on teenagers with mild-to-moderate symptoms in a study, however, the improvements in anxiety and depressive symptoms that the adolescents reported after taking 14 mg of saffron twice a day for eight weeks were inconsistently corroborated by their parents. Although the use of saffron in depression is poorly understood, some research suggests it may work like SSRIs to increase brain levels of serotonin, a chemical known to regulate mood.
When used as a weight-loss aid, saffron supplements are purported to curb appetite and reduce cravings. Some proponents suggest that saffron increases brain levels of serotonin and, in turn, helps prevent compulsive overeating and the associated weight gain.
Saffron extract shows promise as a means of controlling compulsive eating, according to a small study published in Nutrition Research in For the study, healthy women who were mildly overweight took either a saffron-containing supplement or a placebo every day for eight weeks.
Caloric intake was unrestricted. Study results showed that members of the saffron group experienced a significantly greater decrease in snacking and a significantly greater reduction in body weight compared to members of the placebo group. The study's authors note that saffron's supposedly mood-enhancing effects could contribute to the decrease in snacking frequency. Saffron is added as an ingredient in some vision supplements, and several small studies suggest it may be beneficial in the early stages of age-related macular degeneration.
In one randomized, double-blinded, placebo-controlled crossover trial published in , adults with mild-to-moderate AMD were given 20 mg of saffron or a placebo for three months. Researchers concluded that saffron modestly improved visual function and that due to the chronic nature of AMD, longer-term supplementation may produce greater benefits. Preliminary research suggests that saffron may inhibit the aggregation and deposition of beta-amyloid plaques in the human brain and may, therefore, be useful in Alzheimer's disease.
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